Check Following Code: PIL

#[Optional] Images Variables from command arguments

#from sys import argv

#base_image = argv[1]
#test_image = argv[2]
#result_image= argv[3]

#[Main] 

from PIL import Image,ImageChops,ImageOps
from functools import reduce
import math,operator

# Images Variables 
base_image = "1.jpg"
test_image = "2.jpg"
result_image= "result.jpg"

print("-------------------------------- ")
# Base Image 
baseImage = Image.open(base_image).convert('RGB')
print("Base Image = ",base_image , " : ")
print("Width = ",baseImage.width, "Height = ",baseImage.height)

# Test Image 
testImage = Image.open(test_image).convert('RGB')
print("Test Image = ",test_image , " : ")
print("Width = ",testImage.width, "Height = ",testImage.height)

print("================================ ")

#ITechOasis Image Comparision
diff_Image=ImageChops.difference(baseImage, testImage).convert('RGB')

To Change Difference section color :

#Difference in Color
diffInColor = Image.new('RGB', diff_Image.size, 'red')
newDiff = ImageChops.multiply(diffInColor, diff_Image)

To Check % Image Difference:

#Image_Difference
h = newDiff.histogram()
Image_Difference = math.sqrt(reduce(operator.add,map(lambda h, i: h*(i**2), h, range(256))) / (float(baseImage.size[0]) * baseImage.size[1]))

if newDiff.getbbox() is None: 
 newDiff.save(result_image)
 print ("[Pass] Both Images are Same. Image_Difference = ", Image_Difference)
else:
 newDiff.save(result_image)
 print ("[FAIL] Images are Different ! Image_Difference = ", Image_Difference)

print("================================ ")

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